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Just like it is not economical to find a curer for major diseases, it is not economical to find the solutions to the GUT or TOE. We find treatments for diseases, and we find treatments for theoretical physics, but ignore solutions.
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That, in a nutshell, pretty much parallels my thinking on the subject of scientific philosophy and pure math-based theory versus practical science. We find greater interest in the bizarre than in the simple truth.
No doubt we shall always have a theoretical physics so long as there lives a humanity to postulate the stuff of it.