Physics is a study of centers. Some of the centers being studied are:
1. Center of mass
2. Center of charge
3. Center of gravity
4. Center of energy
5. Center of force
6. Center of density
7. Center of volume
8. Center of area
9. Center of nothing, which is the antithesis to the title
10. Etcetera
Archimedes used to say 'give a center (fulcrum) for where to stand and I will move and displace the entire universe.'
the following site shows some images when something is off-centered.
http://en.wikipedia.org/wiki/Center_of_mass