RNA viruses

[AntonioLao]

Common RNA viruses are: (1) Flaviviridae: causes Break Bone Fever carried by mosquitoes and is often fatal, e.g. St. Louis encephalitis and Hepatitis C virus (HCV). (2) Picornavirus: e.g. Poliovirus causes Poliomyelitis includes Hepatitis A virus (HAV) and Rhinovirus causes common cold. (3) Retroviridae: includes HIV and Human T-cell leukemia virus 1 and 2. (4) Togaviruses is carried by mosquitoes and caused severe encephalitis. Rubella virus causes German measles. (5) Orthomytoviruses: e.g. influenza A, B, and C cause localized infections of the respiratory tract, A and B viruses cause inflammations of the nerves, B causes Reyes syndrome lethal to the liver and the brain. (6) Paramyxovirus: e.g. mumps and measles viruses that frequently infect infants and young adults. (7) Rhabdovirus: e.g. rabies by animal bites. In rare cases, a person can be infected by inhaling the virus. ( Filoviridae: e.g. ebola virus causes African hemorrhagic fever.

[labelwench]

The Equine variant of Rhinovirus is of serious concern to horse breeders as it can be the cause of late term abortion in the pregnant mare. Only once have I lost a late term foal to this disease as suspected cause, after which I quarantined my premises for three months to other horses and did not take any of my horses to other premises, although riding, training and other activities continued on location without interruption.

As I currently have a pregnant mare on site, and have discontinued vaccinations due to concerns related to the practice, I am observing Madelaine's growing abdomen with anticipation and awareness that this is her first foal, and there are many complications that can result in not obtaining the desired outcome. Her window of opportunity is may 15th-30th, and we are hopeful that a new foal shall grace our lives.

Abortions caused by EHV1 usually occur in the last 4 months of gestation, but may occur as early as the fourth month. Infection usually occurs 1–4 months prior to abortion and infected mares show no signs of respiratory or other illness. There are usually no complications after the abortion. The foetus is expelled dead, with the foetal membranes intact. Occasionally, when mares are infected late in gestation, infected foals are either stillborn or die within a few days of birth. The conception rate of mares, 30 days after abortion, is high. Abortion occurs most commonly in mares during their first pregnancy. Having once aborted mares usually breed normally in subsequent years, and only rarely abort again.

[AntonioLao]

I'm sure I would like to perform experiments whether modified CH2 solutions can treat RNA viral diseases?

[labelwench]

I'm sure I would like to perform experiments whether modified CH2 solutions can treat RNA viral diseases?

LOL.....You are getting way beyond my level of expertise with that one, Antonio. Our horse veterinary expertise is likewise limited in these parts and the clinics occasionally bring up a breeding and lameness specialist from Texas. One year, we used my stable as his base of operation and people trailered their horses to my facility for his inspections and treatment. I was able to observe a number of diagnosis and the use of an endoscope in examining a horses' esophagus, cortisone injections for joint conditions, use of a portable x-ray etc.

Another of my students went on to become a vet technician and even with the assistance of the local clinic, she was unable to have an artificially inseminated mare carry to term. From my own research and phone calls to outside professionals, I have learned that horse semen is far more fragile than bull semen to transport, thaw and inseminate, so I was not surprised that out of six tries with three mares, over two years, she had no success.

Good luck with your research in the treatment of RNA viral disease, but I am not volunteering any of my horses as subjects. Live and die by the sword in these remote northern parts, lol....

[AntonioLao]

Good luck with your research in the treatment of RNA viral disease

Seriously, I need more than luck. I also need financial backing. But I dont think any pharmaceutical company will buy my half-baked idea.

[labelwench]

Seriously, I need more than luck. I also need financial backing. But I dont think any pharmaceutical company will buy my half-baked idea.

From others have I heard, that the pharmaceutical industry is not interested in funding any research that might negatively influence their share of the market. It is not encouraging to think that the politics of those who have pledged to 'do no harm', are so deeply entrenched in business, where the bottom line is the prime mover. Unless you have a credible hypothesis that may well provide a product or medical service that will improve the present income stream for the company, I can understand that funding may be hard to secure.

Should I win a lottery of any significant size, I would certainly be interested in your research, depending on just how deep of pockets would be required. Money is meant to be put to use, in my opinion. I'd likely need a good accountant and financial advisor, possibly even security, lol.....I'll post the openings on the forum first, should such an unlikely event come to pass.

[AntonioLao]

It seems to me that new scientific discoveries and entrenched big businesses never get along at any later stages of development and implementation of every discovery whether in the biological sciences or in the physical sciences. It is also tempting to say that the rise of corporations somehow discourages the desire for any new discovery. As any progress of society, most are scientifically conservative rather than scientifically radical.

[labelwench]

It seems to me that new scientific discoveries and entrenched big businesses never get along at any later stages of development and implementation of every discovery whether in the biological sciences or in the physical sciences. It is also tempting to say that the rise of corporations somehow discourages the desire for any new discovery. As any progress of society, most are scientifically conservative rather than scientifically radical.

Big business follows as its prophet, the god by the name of "PROFIT", and so, your observation presents as correct, at least to the present time.

Ideologies and gods change over time.

Perhaps change may be effected?

[AntonioLao]

Perhaps change may be effected?

But I'm hoping that these future changes are not similar to the recent financial debacles, both banking system and the automobile industry.

[labelwench]

But I'm hoping that these future changes are not similar to the recent financial debacles, both banking system and the automobile industry.

Change shall have to come from outside the present structures, IMO, otherwise we shall still have those with vested interest merely attempting to 'repackage' the same old goods, and launch same as a 'new product'.

The strategy is used with remarkable success in the grocery industry. Humans are obsessed with novelty, even if it is an illusion.

A difference which makes no difference, is no difference.

Yet, somehow, people seem not to notice. Or perhaps they do notice, and just buy into the game?